Biocompare.com RSS feed http://www.biocompare.com/ © 2010 Biocompare.com Sun, 01 Aug 2010 02:07:52 GMT http://backend.userland.com/rss RSS.NET: http://www.rssdotnet.com/ AUSTIN, Texas-Mutations in a gene known as "Fritz" may be responsible for causing human genetic disorders such as Bardet-Biedl syndrome, University of Texas at Austin developmental biologist John Wallingford and Duke University human geneticist and cell biologist Nicholas Katsanis have found. http://news.biocompare.com/newsstory.asp?id=335983 Biocompare.com Fri, 30 Jul 2010 14:21:00 GMT Louisville, Ky. -- People with a family history of male breast cancer perceive themselves to be at higher risk of developing the disease than do patients with a family history of female breast cancer; however those with male breast cancer in their families are less likely to know about or seek genetic testing than those with a family history of female breast cancer, according to a study led by researchers at the University of Louisville's James Graham Brown Cancer Center. http://news.biocompare.com/newsstory.asp?id=335969 Biocompare.com Fri, 30 Jul 2010 13:43:00 GMT BOSTON -- The recent discovery of more than a thousand genes known as large intergenic non-coding RNAs (or "lincRNAs") opened up a new approach to understanding the function and organization of the genome. That surprising breakthrough is now made even more compelling with the finding that dozens of these lincRNAs are induced by p53 (the most commonly mutated gene in cancer), suggesting that this class of genes plays a critical role in cell development and regulation. Furthermore, the researchers identify one lincRNA in particular (lincRNA-p21), and demonstrate its critical role in suppressing the reading of many genes across the genome following p53 activation. Led by investigators at Beth Israel Deaconess Medical Center (BIDMC) and the Broad Institute, the results are published in the August 6 issue of the journal Cell, which appears on-line today. http://news.biocompare.com/newsstory.asp?id=335957 Biocompare.com Fri, 30 Jul 2010 13:03:00 GMT A genetics research team based at The Children's Hospital of Philadelphia continues to discover recurrent translocations-places in which two chromosomes exchange pieces of themselves. As many as 1 in 600 persons carry balanced chromosome translocations, which involve no loss or gain of DNA. Most such people appear healthy, but may have a child with abnormal chromosome composition and disabilities resulting from disrupted, extra or missing copies of genes. http://news.biocompare.com/newsstory.asp?id=335955 Biocompare.com Fri, 30 Jul 2010 12:59:00 GMT Over millions of years, retroviruses, which insert their genetic material into the host genome as part of their replication, have left behind bits of their genetic material in vertebrate genomes. In a recent study, published July 29 in the open-access journal PLoS Pathogens, a team of researchers have now found that human and other vertebrate genomes also contain many ancient sequences from Ebola/Marburgviruses and Bornaviruses - two deadly virus families. http://news.biocompare.com/newsstory.asp?id=335953 Biocompare.com Fri, 30 Jul 2010 12:30:00 GMT Scientists have successfully used "next generation sequencing" to identify mutations that may cause a rare and mysterious genetic disorder. The research, published by Cell Press on July 29th in the American Journal of Human Genetics, demonstrates that sequencing an affected individual's entire "exome"; that is, all of the genes that carry instructions for producing proteins, can reveal critical genes that when mutant, cause inherited disorders. http://news.biocompare.com/newsstory.asp?id=335948 Biocompare.com Fri, 30 Jul 2010 11:59:00 GMT A team of researchers from leading universities in Turkey and the United States have reported that they have identified the genetic mutation responsible for the Uner Tan Syndrome (UTS) using advanced genetic capture and sequencing technologies from Roche (SIX: RO, ROG; OTCQX: RHHBY). The combined genomic technologies enabled the team of scientists to identify the causative mutation of this debilitating disease after years of mystery. The study was presented by Suleyman Gulsuner, M.D. from Bilkent University, Turkey during the European Human Genetics Conference recently held in Gothenburg, Sweden at which he was awarded the prestigious Isabelle Oberlé Award for outstanding work in the field of genetics of mental retardation. http://news.biocompare.com/newsstory.asp?id=335943 Biocompare.com Fri, 30 Jul 2010 10:49:00 GMT Ever notice some people seem to eat anything they want and never gain a pound, while others seem to gain weight just by looking at fattening foods? You may be seeing things correctly after all. According to research published in the July 2010 issue of Genetics (http://www.genetics.org), this may have a biological cause. Using fruit flies, researchers have found that genes interacting with diet, rather than diet alone, are the main cause of variation in metabolic traits, such as body weight. This helps explain why some diets work better for some people than others, and suggests that future diets should be tailored to an individual's genes rather than to physical appearance. http://news.biocompare.com/newsstory.asp?id=335746 Biocompare.com Thu, 29 Jul 2010 10:23:00 GMT Researchers hoping to simplify their gene expression studies can now watch an instructional video by Bio-Rad that shows best practices from pre-transfection cell counting with an automated cell counter to the analysis of gene expression using real-time PCR. The video, entitled "Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells," is available at http://bit.ly/a3Wroj. http://news.biocompare.com/newsstory.asp?id=335740 Biocompare.com Thu, 29 Jul 2010 08:23:00 GMT The identification of an oncogene (called BRF2) specific to lung squamous cell carcinoma suggests that genetic activation of this oncogene could be used as an identification marker for this type of lung cancer. Furthermore, this oncogene may provide a new target for therapeutics for lung squamous cell carcinoma. These findings come from a study by William Lockwood and colleagues from the BC Cancer Agency's Research Centre in Vancouver, Canada, and are reported in this week's PLoS Medicine. http://news.biocompare.com/newsstory.asp?id=335528 Biocompare.com Wed, 28 Jul 2010 11:11:00 GMT